iLine F

Capturing the Most From Your Suspension Cell Culture Process. In Real-Time.

iLine M

Powerful Cell Confluency Monitoring In Multi-Layer Vessels.

iLine S

The Highest Reproducibly Of Fragile Cell Confluency Monitoring.

QMod

Holographic And Fluorescence Microscopy. In One Single System.

From Intuition to Analytics

Ovizio’s microscopes offer an easy-to-use, label-free and non-invasive tool for the three-dimensional real-time imaging of living cells. Based on patented ‘Differential Digital Holography’ technology, advanced algorithms extract meaningful quantitative data about complex cellular dynamics. Validated with almost every type of transparent cell culture vessel, Ovizio's devices can track cell density, cell morphology as well as cell viability with the highest reproducibility at a single cell level. 

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OVIZIO's microscopes are a particularly convenient and robust solution for automated cell culture monitoring, analysis and quality control. Starting with R&D applications, they can be straightforwardly transferred to manufacturing processes such as in-line solutions for ‘Process Analytical Technology’ plans (PAT). By limiting the number of operations, the related costs are drastically reduced. Improved reproducibility and increased traceability bring our customers to the forefront of today’s Life Science environments.

Case studies

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What people are saying

Eva-Maria Zetsche

Dr, Researcher at the Royal Netherlands Institute

"The qMod has allowed us to investigate marine organisms at high magnification in combination with fluorescence imaging in a simple, easy-to-use manner. In this way we can confirm our observations with the appropriate stains or inherent fluorescence of cells when studying for example, the viability of cells or lipid body content. The ease of use of the instrument and software and support of Ovizio have been most beneficial to our students and us in trying to address key scientific questions."

Jean-Christophe Drugmand

Cell Culture Development Manager, Pall Life Sciences

"I started to collaborate with Ovizio 3 years ago for the integration of their technology to observe human stem cells in Pall Xpansion® multitray bioreactor. It provides key information on cell morphology, confluence and state which is key for cell therapy applications.  Ovizio was chosen for that project because of their innovative technology, the proactivity of its team and its ability to propose us an adapted solution for our specific need."

Sarah Snykers

Senior R&D/QC manager, Promethera Biosciences

Ovizio’s iLineS technology has allowed us to evaluate the confluence in our fully closed multiplate bioreactor system. The direct on-site support, technical hands on and efficient follow-up have been key in reaching this milestone. Currently, Promethera is impatiently looking forward to the release of new tools allowing real-time non-invasive monitoring of apoptosis/phenotypic changes of 2D cultures. This would substantially contribute to the in process and quality control of cell therapeutic products in general    

Philippe Willemsen

Pilot Plant Manager, Promethera Biosciences

While scaling up production process from regular multi-tray stacks to bioreactors, it was an enormous challenge for Ovizio to fill the gap between regular microscopy and alternative cell quality evaluation. The continuous improvement and innovation, as well as close relationship with the end-user are trademarks of Ovizio. Further software upgrades allowing real-time and automated label-free cell count measurements would substantially contribute to the industrialization of Promethera’s manufacturing process.